KISS (Kisspeptin-10)
Kisspeptin signaling peptide · 10mg
99%+ Pure$50
Product Description
Kisspeptin-10 is a bioactive fragment of the kisspeptin family that activates GPR54 (KISS1R) receptors and stimulates the GnRH pathway in research models. Originally identified as a metastasis suppressor gene product, kisspeptin has become a key research tool for investigating neuroendocrine signaling, reproductive axis function, and downstream gonadotropin secretion in controlled laboratory settings.
Expert Insight
“Kisspeptin-10 is used to probe GnRH release and downstream gonadotropin dynamics, enabling researchers to quantify changes in the HPG-axis response and associated endocrine parameters. Its dual discovery as both a metastasis suppressor and neuroendocrine regulator makes it uniquely versatile.”
Research Pairing Suggestions
Researchers studying the full growth hormone axis commonly pair these because kisspeptin stimulates upstream GnRH/gonadotropin release while CJC-1295 activates GHRH-mediated GH secretion, enabling multi-level endocrine investigation.
This combination allows researchers to investigate both the HPG and GH axes simultaneously—kisspeptin drives gonadotropin dynamics while Tesamorelin provides sustained GHRH-analog GH-axis activation.
Research Highlights
Activates GPR54 receptors on GnRH neurons, triggering calcium mobilization and ERK1/2 signaling
Stimulates LH and FSH release in laboratory models of neuroendocrine function
Originally identified as metastasis suppressor — used in cellular proliferation research
This calculator is a math tool only. It does not provide medical advice. Vital Peptides Labs sells research peptides for laboratory and research use only. Users are strongly encouraged to read the linked research, consult qualified professionals, and draw their own conclusions before making any decisions.
Reconstitution Calculator— KISS (Kisspeptin-10)
Research Literature — KISS (Kisspeptin-10)
The following is a summary of published research literature. This information is provided for educational reference only and does not constitute medical advice or research amount guidance.
Research Amounts in Literature
In published studies, researchers have administered kisspeptin-10 at doses of 0.01–10 nmol/kg in animal models. Human research protocols have used intravenous boluses of 0.3–10 µg/kg and subcutaneous doses of 6.4–12.8 nmol/kg.
Frequency Protocols in Research
Published literature on kisspeptin reports single-dose bolus protocols for acute GnRH/LH response studies, and repeated daily administration for sustained HPG-axis investigation over 1–2 week research periods.
Reconstitution Concentrations in Research
Published research reports reconstitution of 10 mg kisspeptin-10 vials in 2–3 mL bacteriostatic water, yielding concentrations of 3.3–5 mg/mL. Using 2 mL (5 mg/mL) is standard for peptide research.
Typical Syringe Ranges in Research
At 5 mg/mL concentration, typical research administration volumes range from 5–20 units (0.05–0.2 mL) on a standard research syringe for microgram-level dosing protocols.
KISS (Kisspeptin-10)
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3mL / 23G Reconstitution Syringe
For mixing bacteriostatic water into lyophilized peptide vials
~$10–15
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For precise subcutaneous administration in research protocols
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For sterilizing vial stoppers and work surfaces
~$5–8
Buy on AmazonBacteriostatic Water (10mL)
Sterile water with 0.9% benzyl alcohol for reconstitution
$10
ViewThis product is intended strictly for laboratory research and development purposes only. Not for human consumption, medical, veterinary, or household use. By purchasing this product, you confirm that you are at least 21 years of age and that the product will be used solely for legitimate research purposes.