KPV
α-MSH tripeptide fragment · 10mg
99%+ Pure$50
Product Description
KPV is a three-amino-acid fragment (Lys-Pro-Val) derived from the C-terminal end of alpha-melanocyte-stimulating hormone (α-MSH). This tripeptide functions as a PepT1-mediated modulator of inflammatory signaling pathways in research models. Researchers use KPV to investigate NF-κB suppression, pro-inflammatory cytokine regulation, and epithelial barrier function in controlled laboratory systems.
Expert Insight
“KPV inhibits NF-κB nuclear translocation and reduces pro-inflammatory cytokine expression without melanocortin receptor activation, enabling targeted mechanistic research on inflammatory signaling. Its small tripeptide structure and PepT1 transporter pathway make it a uniquely efficient research tool.”
Research Pairing Suggestions
Researchers studying immune modulation commonly pair these because KPV provides targeted anti-inflammatory NF-κB suppression while Thymosin Alpha-1 supports broader immune system resilience and function.
Research Highlights
Suppresses NF-κB and MAPK signaling cascades via PepT1 transporter pathway
Demonstrates preserved cell viability with no measurable cytotoxicity in extended exposure models
Modulatory effects on intestinal barrier integrity and pro-inflammatory markers in research models
This calculator is a math tool only. It does not provide medical advice. Vital Peptides Labs sells research peptides for laboratory and research use only. Users are strongly encouraged to read the linked research, consult qualified professionals, and draw their own conclusions before making any decisions.
Reconstitution Calculator— KPV
Research Literature — KPV
The following is a summary of published research literature. This information is provided for educational reference only and does not constitute medical advice or research amount guidance.
Research Amounts in Literature
In published studies, researchers have administered KPV at doses of 10–200 µg in animal models. Research protocols commonly reference doses in the 50–200 µg range for subcutaneous administration.
Frequency Protocols in Research
Published literature on KPV reports once-daily to twice-daily subcutaneous administration protocols in research settings. Study durations typically range from 7–28 days depending on the research model.
Reconstitution Concentrations in Research
Published research reports reconstitution of 10 mg KPV vials in 2–3 mL bacteriostatic water, yielding concentrations of 3.3–5 mg/mL. Using 2 mL (5 mg/mL) provides a practical concentration for microgram-level dosing.
Typical Syringe Ranges in Research
At 5 mg/mL concentration, a 100 µg dose equals 2 units (0.02 mL). Typical research administration volumes range from 1–4 units (0.01–0.04 mL) on a standard research syringe.
KPV
Add to your order
Pairs Well With
You'll Also Need
3mL / 23G Reconstitution Syringe
For mixing bacteriostatic water into lyophilized peptide vials
~$10–15
Buy on Amazon31G Research Syringe
For precise subcutaneous administration in research protocols
~$12–18
Buy on AmazonAlcohol Prep Pads
For sterilizing vial stoppers and work surfaces
~$5–8
Buy on AmazonBacteriostatic Water (10mL)
Sterile water with 0.9% benzyl alcohol for reconstitution
$10
ViewThis product is intended strictly for laboratory research and development purposes only. Not for human consumption, medical, veterinary, or household use. By purchasing this product, you confirm that you are at least 21 years of age and that the product will be used solely for legitimate research purposes.