RESEARCH USE ONLY All products are intended strictly for laboratory research and development purposes. Not for human consumption, medical, veterinary, or household use.
SS-31

SS-31

Mitochondrial-targeting peptide

99%+ Pure

$50

Third-party lab tested
Certificate of Analysis included
Ships within 1 business day
Free shipping on orders over $100

Product Description

SS-31 (Szeto-Schiller 31, also known as Elamipretide) is a small mitochondrial-targeted peptide (H-D-Arg-D-2',6'-dimethyltyrosine-L-Lys-D-Phe-NH2) that accumulates in the inner mitochondrial membrane. This specially designed peptide was engineered to optimize mitochondrial targeting and has been extensively researched for its effects on mitochondrial function and cellular bioenergetics.

Expert Insight

SS-31 represents cutting-edge rational peptide design: engineered specifically to cross membranes and accumulate in mitochondria. Its mitochondrial targeting ability makes it uniquely valuable for investigating inner-membrane dynamics and cellular energy metabolism.

Research Pairing Suggestions

This pairing is valuable in mitochondrial function research because SS-31 protects mitochondrial membrane integrity while MOTS-C regulates metabolic signaling, addressing both structural and functional mitochondrial health.

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Researchers studying mitochondrial bioenergetics commonly pair these because NAD+ supports cellular energy production while SS-31 ensures mitochondrial membrane integrity for optimal energy utilization.

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This combination addresses mitochondrial neuroprotection—SS-31 protects mitochondrial structure while Humanin provides neuroprotective signaling, creating complementary cellular and neurological support.

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Research Highlights

Rationally designed mitochondrial-targeting peptide

Accumulates in inner mitochondrial membrane

Research on cellular bioenergetics and mitochondrial function

This calculator is a math tool only. It does not provide medical advice. Vital Peptides Labs sells research peptides for laboratory and research use only. Users are strongly encouraged to read the linked research, consult qualified professionals, and draw their own conclusions before making any decisions.

Reconstitution CalculatorSS-31

Research Literature — SS-31 (Elamipretide)

The following is a summary of published research literature. This information is provided for educational reference only and does not constitute medical advice or research amount guidance.

Research Amounts in Literature

In published clinical trials, researchers administered Elamipretide at doses of 0.01–0.25 mg/kg IV and 4–40 mg subcutaneously per day. Common subcutaneous research doses are 20–40 mg.

Frequency Protocols in Research

Published literature on SS-31/Elamipretide reports once-daily subcutaneous administration protocols in clinical research, with single-dose and multi-week (28-day) study designs.

Reconstitution Concentrations in Research

Published literature reports reconstitution of 10 mg vials in 2 mL bacteriostatic water (5 mg/mL) and 50 mg vials in 3–5 mL (10–16.7 mg/mL). Higher water volumes reduce viscosity for the larger 50 mg vials.

Typical Syringe Ranges in Research

At 5 mg/mL (10 mg vial in 2 mL), a 20 mg dose requires 4 mL — split across multiple administration sites. At 10 mg/mL (50 mg vial in 5 mL), a 20 mg dose equals 200 units (2.0 mL).

SS-31

Add to your order

$50

Pairs Well With

NAD+

$109

You'll Also Need

3mL / 23G Reconstitution Syringe

For mixing bacteriostatic water into lyophilized peptide vials

~$10–15

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31G Research Syringe

For precise subcutaneous administration in research protocols

~$12–18

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Alcohol Prep Pads

For sterilizing vial stoppers and work surfaces

Bacteriostatic Water (10mL)

Sterile water with 0.9% benzyl alcohol for reconstitution

$10

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This product is intended strictly for laboratory research and development purposes only. Not for human consumption, medical, veterinary, or household use. By purchasing this product, you confirm that you are at least 21 years of age and that the product will be used solely for legitimate research purposes.