RESEARCH USE ONLY All products are intended strictly for laboratory research and development purposes. Not for human consumption, medical, veterinary, or household use.
MOTS-C

MOTS-C

Mitochondrial-optimizing peptide · From 10mg

99%+ Pure

$50

Third-party lab tested
Certificate of Analysis included
Ships within 1 business day
Free shipping on orders over $100

Product Description

MOTS-C (Mitochondrial Open Reading Frame of the Twelve S rRNA Type-C) is a 16-amino acid peptide encoded by the mitochondrial genome. This uniquely positioned peptide functions as a mitochondrial-derived signaling molecule and has attracted significant research attention for its metabolic effects and potential role in cellular homeostasis. MOTS-C represents a new frontier in peptide research focused on mitochondrial-nuclear communication.

Expert Insight

MOTS-C represents a paradigm shift in peptide research: a signal molecule directly encoded by mitochondrial DNA. Its investigation opens new perspectives on mitochondrial-derived factors and their systemic metabolic effects—bridging organellar biology with whole-organism physiology.

Research Pairing Suggestions

Researchers studying mitochondrial metabolism commonly pair these because 5-Amino-1MQ boosts NAD+ while MOTS-C modulates metabolic signaling, creating complementary approaches to metabolic optimization.

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This pairing is valuable in mitochondrial bioenergetics research—MOTS-C regulates metabolic signaling while SS-31 protects mitochondrial membrane integrity, addressing both function and structure.

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Both address mitochondrial energy through complementary mechanisms—NAD+ supports cellular energy pathways while MOTS-C modulates metabolic regulation, making this pairing relevant for mitochondrial function studies.

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Research Highlights

Mitochondrial genome-encoded peptide hormone

Mitochondrial-derived signaling molecule with metabolic effects

Emerging research on mitochondrial-nuclear communication

This calculator is a math tool only. It does not provide medical advice. Vital Peptides Labs sells research peptides for laboratory and research use only. Users are strongly encouraged to read the linked research, consult qualified professionals, and draw their own conclusions before making any decisions.

Reconstitution CalculatorMOTS-C

Research Literature — MOTS-C

The following is a summary of published research literature. This information is provided for educational reference only and does not constitute medical advice or research amount guidance.

Research Amounts in Literature

In published studies, researchers have administered MOTS-C at doses of 5–15 mg/kg in animal models. Human-equivalent research protocols commonly reference 5–10 mg per administration.

Frequency Protocols in Research

Researchers studying MOTS-C have commonly used daily to 3x/week subcutaneous administration protocols over 4–8 week study periods.

Reconstitution Concentrations in Research

Published literature reports reconstitution of 10 mg vials in 2–3 mL bacteriostatic water, yielding concentrations of 3.3–5 mg/mL. Using 2 mL (5 mg/mL) is the most commonly referenced standard.

Typical Syringe Ranges in Research

At 5 mg/mL (2 mL water), a 5 mg dose equals 100 units (1.0 mL). At 3.3 mg/mL (3 mL water), the same dose equals 150 units (1.5 mL) — may require a larger syringe.

MOTS-C

Add to your order

$50

Pairs Well With

NAD+

$109

You'll Also Need

3mL / 23G Reconstitution Syringe

For mixing bacteriostatic water into lyophilized peptide vials

~$10–15

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31G Research Syringe

For precise subcutaneous administration in research protocols

~$12–18

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Alcohol Prep Pads

For sterilizing vial stoppers and work surfaces

Bacteriostatic Water (10mL)

Sterile water with 0.9% benzyl alcohol for reconstitution

$10

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This product is intended strictly for laboratory research and development purposes only. Not for human consumption, medical, veterinary, or household use. By purchasing this product, you confirm that you are at least 21 years of age and that the product will be used solely for legitimate research purposes.