RESEARCH USE ONLY — All products are intended strictly for laboratory research and development purposes. Not for human consumption, medical, veterinary, or household use.
Vital Peptides Labs
Home/Shop Peptides/5-Amino-1MQ
5-Amino-1MQ

5-Amino-1MQ

NAD+ depletion inhibitor · 5mg

99%+ Pure

$75

Third-party lab tested
Certificate of Analysis included
Ships within 1 business day
Free shipping on orders over $100

Product Description

5-Amino-1MQ is a selective inhibitor of NAD+-consuming enzyme nicotinamide N-methyltransferase (NNMT). By inhibiting NNMT activity, 5-Amino-1MQ increases intracellular NAD+ levels and has attracted significant research attention for its metabolic effects. This compound represents a novel pharmacological approach to modulating cellular NAD+ metabolism.

Expert Insight

“As research reveals NNMT's role in aging and metabolic dysfunction, selective NNMT inhibitors like 5-Amino-1MQ have become invaluable tools. By increasing intracellular NAD+ without direct supplementation, 5-Amino-1MQ offers researchers a mechanistic window into endogenous NAD+ metabolism.”

Research Pairing Suggestions

+NAD+

Researchers studying NAD+ metabolism commonly pair these because 5-Amino-1MQ boosts intracellular NAD+ through NNMT inhibition, amplifying NAD+ signaling pathways. This synergy is particularly relevant in studies examining mitochondrial energy and cellular repair.

View
+MOTS-C

Both peptides address mitochondrial function through complementary mechanisms—5-Amino-1MQ elevates NAD+ while MOTS-C modulates metabolic signaling—making their pairing valuable in research exploring metabolic resilience.

View
+SS-31

Researchers studying mitochondrial bioenergetics have paired these to target both NAD+ production (via 5-Amino-1MQ) and mitochondrial membrane protection (via SS-31), creating a dual approach to cellular energy optimization.

View

Research Highlights

Selective NNMT (nicotinamide N-methyltransferase) inhibitor

Increases intracellular NAD+ through metabolic pathway

Peer-reviewed research on NAD+-related aging mechanisms

This calculator is a math tool only. It does not provide medical advice. Vital Peptides Labs sells research peptides for laboratory and research use only. Users are strongly encouraged to read the linked research, consult qualified professionals, and draw their own conclusions before making any decisions.

Reconstitution Calculator— 5-Amino-1MQ

Use our full calculator for all peptides

Research Literature — 5-Amino-1MQ

The following is a summary of published research literature. This information is provided for educational reference only and does not constitute medical advice or research amount guidance.

Research Amounts in Literature

In published studies, researchers have administered 5-Amino-1MQ orally and via subcutaneous administration at doses of 2–50 mg in preclinical models. Research protocols commonly reference 5–25 mg per administration.

Frequency Protocols in Research

Researchers studying 5-Amino-1MQ have commonly used once-daily oral or subcutaneous protocols over 4–12 week periods in metabolic research models.

Reconstitution Concentrations in Research

For research formulations, research literature reports reconstitution of 5 mg vials in 2 mL bacteriostatic water, yielding a concentration of 2.5 mg/mL.

Typical Syringe Ranges in Research

At 2.5 mg/mL, typical subcutaneous administration volumes in research range from 10–50 units (0.1–0.5 mL).

5-Amino-1MQ

Add to your order

$75

Pairs Well With

NAD+

$109

MOTS-C

$49

SS-31 (Elamipretide)

$49

You'll Also Need

3mL / 23G Reconstitution Syringe

For mixing bacteriostatic water into lyophilized peptide vials

~$10–15

Buy on Amazon

31G Research Syringe

For precise subcutaneous administration in research protocols

~$12–18

Buy on Amazon

Alcohol Prep Pads

For sterilizing vial stoppers and work surfaces

~$5–8

Buy on Amazon

Bacteriostatic Water (10mL)

Sterile water with 0.9% benzyl alcohol for reconstitution

$10

View

This product is intended strictly for laboratory research and development purposes only. Not for human consumption, medical, veterinary, or household use. By purchasing this product, you confirm that you are at least 21 years of age and that the product will be used solely for legitimate research purposes.